Especially after Bioshock's release many people want to play the game that inspired it. And while System Shock 2 can run on XP/Vista/Win7 it needs a little help to get there. If you own System Shock 2 and have problems getting it to run, the best point to start is the SS2 Technical FAQ at strangebedfellows.de.
The site also hosts all available modifications for System Shock 2. For starters I recommend SHTUP (System Shock Texture Upgrade Project).
Additionally you'll find there everything System Shock related (Shock Universe Timeline, Game Editor, Ken Levine's SS1/SS2 bridging story, statistics, wallpapers, screensaver, OST, walkthroughs, etc.)
We've built this comprehensive archive over the past 5 years in hopes to preserve one of the greatest and scariest computer games series and enable nostalgic players as well as new generations to experience the System Shock games themselves. Have fun.
Great links. Thanks, kolya!