sir you seem to be new a pc gaming, pc games are installed complety on the hard drive it does not load anything from the disk "in this case it just check for the original disk "

since i own "Battlefield 3 , battlefield bad company 2, medal of honor and Hawx retail version and none of them force me to have the disk in the dvdrom in other to play only bioshock 2

they all use unique key linked to an email acc so yes this problem needs a fix.
ps : im also a proud owner of hawx 2 and assasins greed 2 which use the infamous "always online" ubisoft drm but guess what!? even that is less painful than having the dvd on the dvd room always, also ubisoft patch it and now it LETS YOU PLAY OFFLINE in case you don't have internet access